EPIDEMIOLOGY
Some of Dr. Aplenc's epidemiologic goals include defining and applying ExtractEHR, a software package co-developed for electronic health record data extraction and curation, to address impactful clinical research questions, assessing acute and short term anthracycline associated cardiotoxicity in pediatric AML, and identifying disparities in pediatric cancer outcomes
Miller TP, Getz KD, Li Y, Demissei BG, Adamson PC, Alonzo TA, Burrows E, Cao L, Castellino SM,
Daves MH, Fisher BT, Gerbing R, Grundmeier RW, Krause EM, Lee J, Lupo PJ, Rabin KR, Ramos M,
Scheurer ME, Wilkes JJ, Winestone LE, Hawkins DS, Gramatges MM, Aplenc R. Rates of laboratory
adverse events by course in paediatric leukaemia ascertained with automated electronic health record extraction: a retrospective cohort study from the Children's Oncology Group. Lancet Haematol. 2022 Sep;9(9):e678-e688. PubMed Central PMCID: PMC9444944.
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Miller TP, Li Y, Getz KD, Dudley J, Burrows E, Pennington J, Ibrahimova A, Fisher BT, Bagatell R, Seif
AE, Grundmeier R, Aplenc R. Using electronic medical record data to report laboratory adverse events. Br J Haematol. 2017 Apr;177(2):283-286. PubMed Central PMCID: PMC5384859.
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Miller TP, Li Y, Kavcic M, Troxel AB, Huang YS, Sung L, Alonzo TA, Gerbing R, Hall M, Daves MH,
Horton TM, Pulsipher MA, Pollard JA, Bagatell R, Seif AE, Fisher BT, Luger S, Gamis AS, Adamson
PC, Aplenc R. Accuracy of Adverse Event Ascertainment in Clinical Trials for Pediatric Acute Myeloid Leukemia. J Clin Oncol. 2016 May 1;34(13):1537-43. PubMed Central PMCID: PMC4872308.
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